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Diagnostics and prospective outcome of a diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters after surgical resection (DGONC): a case report

dc.contributor.authorHowie, Chelsea
dc.contributor.authorAhmad, Tahani
dc.contributor.authorMcFadden, Kathryn
dc.contributor.authorCrooks, Bruce
dc.contributor.authorMcNeely, P Daniel
dc.contributor.authorWalling, Simon
dc.contributor.authorRutledge, Robert
dc.contributor.authorSahm, Felix
dc.contributor.authorHinz, Felix
dc.contributor.authorJabado, Nada
dc.contributor.authorKieran, Mark
dc.contributor.authorErker, Craig
dc.date.accessioned2023-01-19T19:39:00Z
dc.date.available2023-01-19T19:39:00Z
dc.date.issued2022-10-25
dc.description.abstractDiffuse glioneuronal tumors with oligodendroglioma-like features and nuclear clusters (DGONC) are rare tumors of the central nervous system, having been added as a provi-sional diagnosis in the 2021 World Health Organization (WHO) Classification of Tumors of the central nervous system (CNS).1Retrospective studies report that these are most often mis-diagnosed and treated as high-grade tumors of the CNS.2,3However, this entity has demonstrated superior long-term survival in comparison. Given its novelty, there is currently no standard of care. We describe the diagnostic challenges, mo-lecular characteristics, prospective management, and outcome of a pediatric patient with a DGONC, with the aim to increase awareness of this entity and describe clinical behavior and di-agnostic uncertainties.en_US
dc.identifier.citationHowie C, Ahmad T, McFadden K, Crooks B, McNeely PD, Walling S, Rutledge R, Sahm F, Hinz F, Jabado N, Kieran M, Erker C. Diagnostics and prospective outcome of a diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters after surgical resection (DGONC): a case report. Neurooncol Adv. 2022 Oct 25;4(1):vdac170. doi: 10.1093/noajnl/vdac170. PMID: 36479060; PMCID: PMC9719366.en_US
dc.identifier.urihttp://hdl.handle.net/10222/82224
dc.publisherOxford University Pressen_US
dc.relation.ispartofNeuro-Oncology Advancesen_US
dc.rights.licenseLicensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleDiagnostics and prospective outcome of a diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters after surgical resection (DGONC): a case reporten_US
dc.typeTexten_US

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