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Antimicrobial Activity of Non-natural Prodigiosenes

Date

2013

Authors

Marchal, E.
Uddin, Md. I.
Smithen, D. A.
Hawco, C. L.A.
Lanteigne, M.
Overy, D. P.
Kerr, R. G.
Thompson, A.

Journal Title

Journal ISSN

Volume Title

Publisher

RSC Advances

Abstract

Tripyrrolic prodigiosenes, derivatives of the natural product prodigiosin, have been produced via multi-step synthesis beginning with 2-formyl pyrroles bearing various functionalities at the 4-position. Two tin complexes are also reported, and these feature a prodigiosene ligand bearing a conjugated benzyl-ester. Antimicrobial activities of prodigiosenes are evaluated against Gram positive and Gram negative bacterial strains, as well as a yeast.

Description

Post-print

Keywords

Citation

Marchal, E., Uddin, M. I., Smithen, D. A., Hawco, C. L. A., Lanteigne, M., Overy, D. P., ... & Thompson, A. (2013). Antimicrobial activity of non-natural prodigiosenes. Rsc Advances, 3(45), 22967-22971. DOI: 10.1039/c3ra45479g

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