dc.contributor.author | Penney, Jasmine | |
dc.date.accessioned | 2023-08-31T17:02:44Z | |
dc.date.available | 2023-08-31T17:02:44Z | |
dc.date.issued | 2023-08-30 | |
dc.identifier.uri | http://hdl.handle.net/10222/82906 | |
dc.description.abstract | Brachytherapy patients with asymmetric gynecological targets are often planned with vendor-supplied applicators and templates, known as the Miami or MUPIT applicator. This research designed multi-catheter applicators with patient-specific catheter positions, which could be created using a 3D printer. In this retrospective REB approved study, twenty-five past patients who received vaginal brachytherapy at the QEII Cancer Centre were chosen. The catheters were reconstructed according to the patient’s anatomy. DVH parameters were compared for the patient-specific applicator and original applicator treatment plans. The high dose regions for all plans showed a decrease for the patient-specific with V200 decreasing from 7.4% to 3.3% (p<0.0001), for an intracavitary applicator. For the interstitial plans, V150 decreased from 38.6% to 34.0% (p<0.0006) for the patient-specific applicators. The quality indices were statistically better for the patient-specific plans. When comparing applicator design, a patient-specific, applicator resulted in better coverage of the CTV, with improved sparing of the OARs. | en_US |
dc.language.iso | en | en_US |
dc.subject | Gynecological brachytherapy | en_US |
dc.subject | patient-specific applicator | en_US |
dc.title | DESIGN OF 3D-PRINTED MULTI-CATHETER GYNECOLOGICAL BRACHYTHERAPY APPLICATORS WITH CUSTOMIZABLE CATHETER POSITIONS | en_US |
dc.type | Thesis | en_US |
dc.date.defence | 2023-08-15 | |
dc.contributor.department | Department of Physics & Atmospheric Science | en_US |
dc.contributor.degree | Master of Science | en_US |
dc.contributor.external-examiner | N/A | en_US |
dc.contributor.graduate-coordinator | Tom Duck | en_US |
dc.contributor.thesis-reader | Dr. Alasdair Syme | en_US |
dc.contributor.thesis-reader | Dr. Amanda Cherpak | en_US |
dc.contributor.thesis-supervisor | Dr. Krista Chytyk-Praznik | en_US |
dc.contributor.ethics-approval | Received | en_US |
dc.contributor.manuscripts | No | en_US |
dc.contributor.copyright-release | Not Applicable | en_US |