dc.contributor.author | Northway, Cassidy | |
dc.date.accessioned | 2020-08-17T12:41:00Z | |
dc.date.available | 2020-08-17T12:41:00Z | |
dc.date.issued | 2020-08-17T12:41:00Z | |
dc.identifier.uri | http://hdl.handle.net/10222/79656 | |
dc.description.abstract | This thesis presents a system that determined patient-specific collision zones (CZs) to enable safe and deliverable non-coplanar treatment trajectories for stereotactic body radiation therapy (SBRT) patients. Full body scans of patients in treatment position were acquired using an optical scanner, creating a library of scans to augment CT scans. This resulted in a patient model that was aligned with a model of the treatment LINAC, where both components were rotated to test for collisions. To test collision detection accuracy an end-to-end cranial test was performed. The buffer sized required during the registration process to achieve a sensitivity of one was determined via a registration accuracy test. Incorporating the patient-specific CZs, non-coplanar treatment plans were created and compared to clinical coplanar plans for SBRT lung patients (N = 8). A statistically significant change in the mean dose to the lungs was found. Our study indicated that determining patient-specific CZs can be accomplished enabling safe non-coplanar treatment plans. | en_US |
dc.language.iso | en | en_US |
dc.subject | Medical Physics | en_US |
dc.subject | Stereotactic Body Radiation Therapy | en_US |
dc.title | Patient-Specific Collision Zones for 4π Trajectory Optimized Radiation Therapy | en_US |
dc.type | Thesis | en_US |
dc.date.defence | 2020-08-05 | |
dc.contributor.department | Department of Physics & Atmospheric Science | en_US |
dc.contributor.degree | Master of Science | en_US |
dc.contributor.external-examiner | n/a | en_US |
dc.contributor.graduate-coordinator | Dr. Theodore Monchesky | en_US |
dc.contributor.thesis-reader | Dr. Alasdair Syme | en_US |
dc.contributor.thesis-reader | Dr. Krista Chytyk-Praznik | en_US |
dc.contributor.thesis-supervisor | Dr. Christopher Thomas | en_US |
dc.contributor.ethics-approval | Received | en_US |
dc.contributor.manuscripts | Not Applicable | en_US |
dc.contributor.copyright-release | Not Applicable | en_US |