Browsing by Subject "mTOR"
Now showing items 1-3 of 3
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Effects of LPS-induced maternal immune activation on expression of autism-linked genes and autism-like behaviours in neonates and adulthood. Towards a maternal infection model of idiopathic autism
(2018-08-13)Epidemiological studies have revealed a link between maternal immune activation (MIA) and autism-spectrum disorder (ASD) risk. In support of this, the offspring of dams exposed to LPS during pregnancy develop ASD-like ... -
Effects of prenatal stress and/or forebrain ATRX deficiency in C57Bl/6 mice on regulation and expression of Autism risk genes
(2020-06-16)Early life experiences influence brain development and consequently, behaviour into adulthood. In humans, maternal stress during the third trimester has been associated with increased incidences of Autism Spectrum Disorder ... -
LOSS OF LKB1 TUMOUR SUPPRESSOR FUNCTION PLAYS A ROLE IN MAMMARY GLAND TUMOURIGENESIS AND REGULATION OF CELL METABOLISM.
(2016-08-05)The tumour suppressor kinase LKB1 is involved in many signalling pathways. LKB1 is particularly important for the regulation of cell homeostasis through the phosphorylation of the metabolic regulator, AMPK. Mutations in ...