Browsing by Subject "biomaterials"
Now showing items 1-5 of 5
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Aciniform Spider Silk Proteins: Investigating Solution-State Assembly and the Potential of Silk Nanoparticles as a Drug Delivery Vehicle
(2021-02-01)Spider and silkworm silks form a wide variety of biomaterials with desirable mechanical properties and biocompatibility. The process of fibrillogenesis from silk solution is not fully understood, but may be dependent on ... -
DISULPHIDE LOCKING: CONTRASTING EFFECTS ON DISPARATE PROTEINS
(2021-12-17)This thesis details a series of structural and biophysical studies on two different proteins containing disulphide bonds: (1) soricidin and (2) engineered mutants of aciniform spider silk. All studies relied upon recombinant ... -
Modeling the prostate cancer tissue microenvironment using hyaluronan hydrogels
(2020-04-14)Prostate cancer cells exist in dynamic, evolving tissue environments and their behaviour is influenced by context-specific interactions with their surroundings. To better understand how and why prostate cancer cells behave ... -
On Light and Matter: Structural Optics of Biomaterials
(2022-04-12)The wings of a morpho butterfly exhibit a dazzling display of crystalline blue that transforms with viewing angle. The optical properties demonstrated by this improbable blue are produced not by pigment but as a function ... -
Strontium releasing composite resin cements
(2019-11-28)While vertebroplasty has proven effective in relieving pain and stabilizing fractures in osteoporotic patients, it currently fails to address the underlying pathology. Strontium releasing composite resin cements, based on ...