Browsing by Subject "Optogenetics"
Now showing items 1-4 of 4
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Characterizing Mouse V1 Optogenetic-Mediated Rebound Effects
(2023-08-28)Cortical circuits comprise excitatory pyramidal (Pyr) cells and inhibitory interneurons that work together to perform neural computations. Optogenetic studies in mouse primary visual cortex (V1) have focused on (i) sketching ... -
Development of a novel in vitro model system to characterize the role of activity in motor neurons during development and disease
(2017-05-11)Neural activity modulates motor axon guidance and synaptic function during development. Differences in neural activity also contribute to the demise of specific motor neuron subtypes in amyotrophic lateral sclerosis (ALS). ... -
Optogenetic Tachypacing-induced Heart Failure in Larval Zebrafish
(2023-07-25)Chronic tachypacing is commonly used in mammals to model heart failure (HF). Alternative methods of chronic tachypacing involving the use of light-activated ion channels (‘optogenetics’) have been explored in cultured heart ... -
THE ZEBRAFISH AS A MODEL FOR STUDIES OF CARDIAC MECHANO-ELECTRIC FUNCTION
(2023-01-10)Factors affecting cardiac function include those external to the heart (e.g., the autonomic nervous system, ANS) and intrinsic processes that allow rapid beat-by-beat adaptation to change in physiological demands. The ...