Browsing by Subject "Microbiology"
Now showing items 1-7 of 7
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Carvacrol possesses anti-bacterial activity against Streptococcus pyogenes and inflammation.
(2022-12-07)Streptococcal pharyngitis, caused by Streptococcus pyogenes, is a significant health issue worldwide. Beta-lactam antibiotics and non-steroidal anti-inflammatory drugs are recommended for treatment and pain management. ... -
FUNCTIONAL INTERPLAY OF INFLUENZA A VIRUS NS1 AND PA-X PROTEINS MEDIATES HOST SHUTOFF
(2022-11-18)Host shutoff is a mechanism to inhibit gene expression and limit the innate immune response. IAV produces two host shutoff proteins: PA-X and NS1. PA-X is an endonuclease that targets and cleaves host mRNAs. NS1 limits ... -
IDENTIFCATION OF ROBUST BIOMARKERS USING MICROBIOME DNA SEQUENCING WITH A FOCUS ON THE ORAL MICROBIOME AND CANCER ASSOCIATIONS
(2022-12-15)High-depth sequencing of universal marker genes such as the 16S rRNA gene is a common strategy to profile microbial communities. Traditionally, sequence reads are clustered into operational taxonomic units (OTUs) at a ... -
INFLUENZA A VIRUS INFECTION AND UFMYLATION
(2024-06-23)This thesis investigates the interplay between UFMylation, a post-translational modification involving the conjugation of the ubiquitin-like protein Ubiquitin-fold modifier 1 (UFM1) to target proteins, and the replication ... -
Mechanisms by which Shigella flexneri impairs dendritic cell function: silencing the link between innate and adaptive immunity
(2015)Shigella flexneri is a Gram-negative bacterial pathogen that causes severe gastroenteritis in humans. Upon infection, Shigella invades the host colonic epithelium using a type III secretion system (T3SS) that is encoded ... -
Mechanistic Contributions of the p10 FAST Protein Ectodomains to Membrane Fusion and Syncytiogenesis
(2013-12-16)The homologous p10 fusion-associated small transmembrane (FAST) proteins of the fusogenic avian (ARV) and Nelson Bay (NBV) reoviruses are the smallest known proteins capable of mediating syncytiogenesis. Their extremely ... -
Nova Scotia Medical Bulletin 30(10), 1951
(Medical Society of Nova Scotia, 1951)