Browsing by Subject "Epigenetic"
Now showing items 1-2 of 2
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ALL-TRANS RETINOIC ACID AND ARSENIC TRIOXIDE INDUCE LASTING DIFFERENTIATION AND DEMETHYLATION OF TARGET GENES IN ACUTE PROMYELOCYTIC LEUKEMIA
(2019-11-28)Acute promyelocytic leukemia (APL) patients treated with all-trans retinoic acid (ATRA) experience relapse, while patients treated with ATRA and arsenic trioxide (ATO) are often relapse-free. To understand combination ... -
SEX, STRESS AND HORMONES: INVESTIGATING THE ROLE OF THE EARLY ENVIRONMENT IN SHAPING BRAIN AND BEHAVIOUR CHANGES LINKED TO NEUROPSYCHIATRIC DISORDERS
(2016-04-05)Vulnerability to anxiety and depression are linked with both sex differences and early life stress. Though human studies suggest that childhood symptoms and neurophysiological markers may predict some adult neuropsychiatric ...