Browsing by Subject "Cystic Fibrosis"
Now showing items 1-5 of 5
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ACE2 and TMPRSS2 Expression and Localization in Cystic Fibrosis Lungs: Potential Role in SARS-CoV-2 Susceptibility
(2024-08-21)COVID-19 results from infection by the SARS-CoV-2 virus and causes mild to severe illness. Clinical reports indicate that many severely ill patients present with co-morbidities including severe lung diseases. However, ... -
CHANGES IN VASOACTIVE INTESTINAL PEPTIDE (VIP) AMOUNT IN CYSTIC FIBROSIS
(2020-12-18)Cystic Fibrosis (CF) is the most common lethal genetic disease in Caucasians, which results from mutations in the CFTR gene. Cystic Fibrosis - Related Diabetes (CFRD) affects more than 50% of adults with CF. The complex ... -
Increased VIP Receptor Expression Mediates CFTR Membrane Localization in Response to VIP Treatment in VIP Knockout Mice
(2011-09-06)Cystic Fibrosis (CF) is caused by mutations in CFTR, a protein for chloride efflux in epithelial cells. VIP is a peptide that activates CFTR and improves membrane stability; VIP has 3 receptors VPAC1, VPAC2 and PAC1 that ... -
Nova Scotia Medical Bulletin 38(5), 1959
(Medical Society of Nova Scotia, 1959) -
Role of Iron Chelation in Inflammation and Infection
(2021-09-14)Iron is an essential element for most forms of life, as its redox-cycling capabilities enable its participation in numerous physiological reactions. However, iron levels must be tightly regulated to avoid free iron toxicity ...