Browsing by Subject "Amyotrophic lateral sclerosis"
Now showing items 1-2 of 2
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IN VITRO MODEL SYSTEMS FOR INVESTIGATION OF MOTONEURON DEVELOPMENT AND DISEASE
(2016-08-12)Spinal motoneurons innervate muscle fibres and represent the final component in the motor pathway responsible for producing movement by eliciting muscle contraction. Although the anatomy and physiology of motoneurons have ... -
Locomotor Compensation for Severe Motor Neuron Loss during Amyotrophic Lateral Sclerosis Disease Progression
(2018-01-05)Amyotrophic lateral sclerosis (ALS) causes progressive motor neuron (MN) degeneration leading to muscle weakness, paralysis, and eventually death. When symptoms are detected in ALS patients and model animals (SOD1G93A mice) ...