Browsing by Subject "Aging"
Now showing items 1-20 of 23
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THE ASSOCIATION BETWEEN SELF-RATED HEALTH AND KEY INDICATORS OF HEALTH IN AN OLDER POPULATION: ANALYSIS OF THE CANADIAN LONGITUDINAL STUDY ON AGING
(2021-09-14)Self-sated health (SRH) is a global indicator of health which reflects a person’s integrated perception of their own health. To obtain an in depth understanding of SRH, this study examined the association between SRH and ... -
Characterization of Cholinergic, Neuropathological, and Neuroinflammatory Changes in Human Brain Nuclei Involved in the Sleep-Wake Cycle in Neurodegenerative Disorders
(2024-08-16)Neurodegenerative disorders (NDDs) embody the progressive loss of structure or function of neurons, typically culminating in neuronal cell death and include conditions such as Alzheimer’s disease (AD), dementia with Lewy ... -
Clinicopathological Correlates in Tauopathy and Aging
(2022-08-16)Cognitive decline can result from both neurodegenerative or normal aging processes. Definitive diagnosis of many neurodegenerative diseases, such as Alzheimer’s disease (AD) and progressive supranuclear palsy (PSP), requires ... -
Developing computational models to understand aging
(2021-12-17)Aging in biological organisms is a complex process, involving changes at all levels of functioning. No single pathway or mechanism is responsible for aging, leading to the current understanding that aging is due to a number ... -
Development of Adhesion Force microscopy for the surface charge analysis of collagen fibrils in vivo and in vitro
(2023-06-12)Collagen fibrils are a key component of the extracellular matrix. In this study, we use the adhesion force between a silicon probe and a collagen substrate to demonstrate the sensitivity of adhesion force towards charge ... -
DRUG USE AND AGE ALTERS THE DRUG METABOLISM POTENTIAL OF THE HUMAN GUT MICROBIOME
(2016-08-23)While drugs play an important role in human health, the interaction between the human microbiome and the metabolism of drugs remains relatively unknown. Studies have demonstrated the microbiome's capability to metabolize ... -
THE EFFECT OF HEALTHY AGING ON TRUNK NEUROMUSCULAR ACTIVATION PATTERNS DURING A CONTROLLED FUNCTIONAL TRANSFER TASK
(2013-04-08)Healthy aging is associated with an increased incidence of injuries such as low back pain and falling. Age-related changes in trunk neuromuscular activation patterns could potentially explain uncontrolled trunk motion, a ... -
Experiences of Food Insecurity Among Older Women in Rural Nova Scotia
(2018-12-17)Older, rural-dwelling women in Canada are at risk of food insecurity, given their longer life spans and vulnerability to poverty; however, there is little research exploring their experiences. Nova Scotia is of interest ... -
Experiences of Health and Aging: Younger Adults with Disabilities in Long-term Care Facilities
(2017-08-31)Canada’s 2011 census revealed that Nova Scotia comprises the largest proportion of people over the age of 65 and the highest proportion of people living with a disability (Statistics Canada, 2012; Statistics Canada, 2013). ... -
EXPLORING HOW CURRENT FEDERAL, PROVINCIAL, AND FIRST NATIONS GOVERNMENT POLICIES SUPPORT AND PROMOTE HEALTHY AGING AMONG OLDER MI’KMAQ IN ATLANTIC CANADA
(2019-08-29)Older Indigenous peoples in Canada, including Mi’kmaq in the Atlantic region, face significant health disparities that occur earlier and more often than for non-Indigenous Canadians. These health disparities mask the unique ... -
EXPLORING TRANSIENT NEURAL EVENTS IN HEALTHY POPULATIONS USING NON-INVASIVE NEUROIMAGING
(2022-08-22)Non-invasive neurophysiological recordings, like those measured by magneto/electro- encephalography (M/EEG), provide insight into the behaviour of neural networks and how these networks change with factors such as task ... -
A GENDER-BASED MULTI-METHODS SECONDARY STUDY OF AGE STEREOTYPES
(2020-06-25)With the aging population, it is vital to understand how the psychosocial environment influences the well-being of the population. Aging is more than just physical change; it is also a psychosocial construct. Age-based ... -
In My Place: Fostering Connection and Continuity in Canada's Aging Rural Communities
(2024-04-11)Facing Canada's demographic shift toward an aging population, this thesis addresses the challenges of aging in rural communities, where services for older adults are often lacking. This thesis proposes intergenerational ... -
Integrating Frailty and Physical Resilience to Improve Risk Estimation in Aging Populations
(2024-04-11)Background: Physical resilience, broadly defined as the ability to resist or recover from health stressors, is a relatively new concept in the field of aging, yet, anticipated as a potentially game-changing idea. In ... -
Investigating the role of frailty in the expression of dementia
(2020-08-28)Background: Frailty is related to neuropathological features of Alzheimer’s disease (AD) as well as cognitive decline and dementia. Objectives: 1) determine whether frailty moderates the relationship between neuropathology ... -
Lesbian, Bisexual, and Two-Spirit Women’s Experiences of Congregate Later-Life Housing in an Atlantic Canadian Continuing Care Organization
(2024-08-14)As the Baby Boomer generation reaches old age, there is increased demand for later-life housing options that reflect their unique cultural context. Therefore, it is vital to consider the experiences of LGBT and Queer Baby ... -
Predictive modeling of damage and repair for disease and activity of daily living status in ELSA dataset using machine learning models
(2023-12-08)A good predictive model is useful in health sciences for predicting onset of disease, as well as damage or repair of health deficits. One can predict one or more of these quantities depending on the nature of the collected ... -
Psychometric Properties and Age-Related Effects of the Combined Attention Systems Test
(2023-04-25)Attention is a multifaceted cognitive process that is important for functioning in daily life. The study of attention commonly focuses on three networks: alerting, orienting, and executive control. Despite the rich literature ... -
The relationship between frailty and the development and progression of HIV-Associated Neurocognitive Disorder (HAND)
(2021-04-12)Background: The objective of this study was to determine the relationship between frailty and the development and progression of HIV-Associated Neurocognitive Disorder (HAND). Methods: This study used data from the ... -
THE RELATIONSHIP BETWEEN HEARING AND FUNCTIONAL MOBILITY AMONG OLDER ADULTS AT BASELINE IN THE CANADIAN LONGITUDINAL STUDY ON AGING
(2021-08-31)Mobility problems, prevalent among older adults, are influenced by numerous factors that are interrelated. The primary purpose was to examine the relationship between hearing, measured by Pure-Tone Audiometry, and mobility, ...