dc.contributor.author | McCann, Bernadette | |
dc.date.accessioned | 2022-12-19T12:40:40Z | |
dc.date.available | 2022-12-19T12:40:40Z | |
dc.date.issued | 2022-12-16 | |
dc.identifier.uri | http://hdl.handle.net/10222/82178 | |
dc.description.abstract | Walking is prescribed for knee osteoarthritis management but evidence to support specific walking prescriptions is lacking. Given that osteoarthritis manifests itself differently between sexes, are sex-specific walking prescriptions needed? This study determined differences between sexes in pain, moment and muscle activation responses to a 30-minute walk in individuals with radiographic knee osteoarthritis, and whether muscle strength explained variability in responses. Forty-five (23 females) participants with radiographic medial knee osteoarthritis were included. Independent t-tests determined males had higher strength, knee flexion moment-knee extension moment difference, and lower pain sensitization and muscle activity than females (p<0.05). Two-way mixed ANOVAs found significant sex by time interactions (p<0.1) where males, but not females, increased their pain sensitization and knee adduction moment (KAM) features post-walk. Linear regression models indicated strength explained 11% of the variance in KAM 1st peak response. Different magnitudes and directions in responses between sexes support the need for sex-specific walking prescriptions. | en_US |
dc.language.iso | en | en_US |
dc.subject | osteoarthritis | en_US |
dc.subject | muscle strength | en_US |
dc.subject | sex | en_US |
dc.subject | walking responses | en_US |
dc.subject | gait analysis | en_US |
dc.title | SEX DIFFERENCES IN KNEE OSTEOARTHRITIS PROCESSES: THE ROLE OF MUSCLE STRENGTH IN EXPLAINING ACUTE PAIN INTENSITY, PAIN SENSITIZATION, KNEE JOINT MOMENT AND MUSCLE ACTIVATION RESPONSES TO A STANDARD CONTINUOUS WALK | en_US |
dc.date.defence | 2022-12-12 | |
dc.contributor.department | School of Biomedical Engineering | en_US |
dc.contributor.degree | Master of Applied Science | en_US |
dc.contributor.external-examiner | n/a | en_US |
dc.contributor.graduate-coordinator | Dr. Jeremy Brown | en_US |
dc.contributor.thesis-reader | Dr. William Stanish | en_US |
dc.contributor.thesis-reader | Dr. Derek Rutherford | en_US |
dc.contributor.thesis-reader | Dr. Janie Astephen Wilson | en_US |
dc.contributor.thesis-supervisor | Dr. Cheryl Kozey | en_US |
dc.contributor.ethics-approval | Received | en_US |
dc.contributor.manuscripts | Not Applicable | en_US |
dc.contributor.copyright-release | Not Applicable | en_US |